Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028947 | 0.81 | GRM5 (0.37) | FFAR1OPRM1OPRL1 | |
| SCHEMBL1352509 | 0.79 | OPRL1 (0.39) | DAGLAOPRM1OPRL1 | |
| SCHEMBL1907283 | 0.78 | VNN1 (0.34) | FFAR1OPRM1OPRL1 | |
| SCHEMBL2030849 | 0.77 | OPRL1 (0.38) | OPRM1OPRL1 | |
| SCHEMBL1908467 | 0.77 | CYP1A2 (0.37) | FFAR1PTGESOPRM1OPRL1 | |
| SCHEMBL2508530 | 0.74 | OPRL1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL1900539 | 0.74 | ACACB (0.30) | — | |
| SCHEMBL1900125 | 0.72 | CTSL (0.32) | OPRM1OPRL1 | |
| SCHEMBL1352136 | 0.71 | CCR2 (0.43) | OPRM1 | |
| SCHEMBL1903372 | 0.70 | OPRM1 (0.30) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055115-A1 | AKT / PKB INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |