L-Fucose

L-Fucose

SCHEMBL18992533

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.67
▸ FUT5 Q11128 1/20 0.62
▸ NT5E P21589 1/20 0.62
▸ KRAS P01116 5/20 0.62
▸ P2RY6 Q15077 2/20 0.58
▸ P2RY2 P41231 1/20 0.58
▸ P2RY4 P51582 1/20 0.58
▸ IMPDH2 P12268 4/20 0.58
▸ DCPS Q96C86 1/20 0.57
▸ ENPP1 P22413 2/20 0.57
▸ P2RY1 P47900 2/20 0.57
▸ P2RY12 Q9H244 1/20 0.57
▸ P2RX3 P56373 2/20 0.56
▸ P2RX1 P51575 1/20 0.56
▸ P2RY11 Q96G91 1/20 0.56
▸ P2RX4 Q99571 1/20 0.56
▸ IMPDH1 P20839 2/20 0.56
▸ HINT1 P49773 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Fucose SCHEMBL20607674 1.00 TGM2 (0.67) TGM2FUT5NT5EKRASP2RY6
L-Fucose SCHEMBL29216038 0.97 TGM2 (0.63) TGM2FUT5NT5EKRASP2RY6
Demannose SCHEMBL2182862 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Glucuronic Acid SCHEMBL27957333 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Demannose SCHEMBL5163477 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Demannose SCHEMBL4290630 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Galactose SCHEMBL6046113 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Demannose SCHEMBL20746287 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Glucuronic Acid SCHEMBL6046180 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6
Glucuronic Acid SCHEMBL5941537 0.92 TGM2 (0.66) TGM2FUT5NT5EKRASP2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572548-B2 Reaction mixture for synthesis of alpha1-2-fucosides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-02-07 — — US disclosed
US-20180371432-A1 TE2FT ENZYME FOR ENZYMATIC SYNTHESIS OF ALPHA1-2-FUCOSIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-12-27 — — US disclosed
WO-2017106864-A1 TE2FT ENZYME FOR ENZYMATIC SYNTHESIS OF ALPHA1-2-FUCOSIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-22 — — WO disclosed
Send feedback