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Sugi Predict / Compounds / Glucuronic Acid

Glucuronic Acid

Glucuronic Acid

SCHEMBL27957333

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=CC(O)C(O)C(O)C(O)C(=O)O

nearest known ligand 0.66

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.66
▸ KRAS P01116 8/20 0.63
▸ NT5E P21589 1/20 0.61
▸ FUT5 Q11128 1/20 0.60
▸ P2RY2 P41231 1/20 0.57
▸ P2RY4 P51582 1/20 0.57
▸ P2RY6 Q15077 1/20 0.57
▸ IMPDH2 P12268 3/20 0.57
▸ P2RX3 P56373 1/20 0.55
▸ IMPDH1 P20839 1/20 0.55
▸ DCPS Q96C86 1/20 0.55
▸ ENPP1 P22413 1/20 0.54
▸ P2RY1 P47900 1/20 0.54
▸ P2RY12 Q9H244 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glucuronic Acid SCHEMBL5941537 1.00 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Glucuronic Acid SCHEMBL6046180 1.00 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
L-Fucose SCHEMBL20607674 0.92 TGM2 (0.67) TGM2KRASNT5EFUT5P2RY2
L-Fucose SCHEMBL18992533 0.92 TGM2 (0.67) TGM2KRASNT5EFUT5P2RY2
Demannose SCHEMBL2182862 0.92 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Galactose SCHEMBL6046113 0.92 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Demannose SCHEMBL20746287 0.92 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Demannose SCHEMBL4290630 0.92 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Demannose SCHEMBL5163477 0.92 TGM2 (0.66) TGM2KRASNT5EFUT5P2RY2
Xylose SCHEMBL1422097 0.91 TGM2 (0.67) TGM2KRASNT5EFUT5P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114813997-B Bile acid marker composition, application and serum detection kit 云谱康(大连)生物科技有限公司 2024-02-13 — — CN disclosed
CN-114813997-A Bile acid marker composition, application and serum detection kit 云谱康(大连)生物科技有限公司 2022-07-29 — — CN disclosed
CN-103710369-B Bifunctional enzyme gene for kelp mannose 6-phosphate isomerization and GDP (Guanosine Diphosphatemannose)-mannose pyrophosphorylation OCEAN UNIV CHINA 2015-07-15 — — CN disclosed
CN-103710369-A Bifunctional enzyme gene for kelp mannose 6-phosphate isomerization and GDP (Guanosine Diphosphatemannose)-mannose pyrophosphorylation OCEAN UNIV CHINA 2014-04-09 — — CN disclosed