Sugi Predict

Sugi Predict / Compounds / Demannose

Demannose

Demannose

SCHEMBL4290630

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.66
▸ NT5E P21589 1/20 0.61
▸ KRAS P01116 6/20 0.61
▸ FUT5 Q11128 1/20 0.60
▸ P2RY6 Q15077 2/20 0.59
▸ P2RY2 P41231 1/20 0.59
▸ P2RY4 P51582 1/20 0.59
▸ IMPDH2 P12268 4/20 0.57
▸ P2RX3 P56373 2/20 0.55
▸ IMPDH1 P20839 1/20 0.55
▸ DCPS Q96C86 1/20 0.55
▸ ENPP1 P22413 2/20 0.54
▸ P2RY1 P47900 2/20 0.54
▸ P2RY12 Q9H244 1/20 0.54
▸ P2RX1 P51575 1/20 0.54
▸ P2RY11 Q96G91 1/20 0.54
▸ P2RX4 Q99571 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL2182862 1.00 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY6
Galactose SCHEMBL6046113 1.00 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY6
Demannose SCHEMBL5163477 1.00 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY6
Demannose SCHEMBL20746287 1.00 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY6
Xylose SCHEMBL1422097 0.98 TGM2 (0.67) TGM2NT5EKRASFUT5P2RY6
Guanosine Triphosphate SCHEMBL27608840 0.97 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY6
Guanosine Triphosphate SCHEMBL29280175 0.95 TGM2 (0.68) TGM2NT5EKRASFUT5P2RY6
Guanosine Triphosphate SCHEMBL28337848 0.93 TGM2 (0.60) TGM2NT5EKRASFUT5P2RY6
L-Fucose SCHEMBL18992533 0.92 TGM2 (0.67) TGM2NT5EKRASFUT5P2RY6
L-Fucose SCHEMBL20607674 0.92 TGM2 (0.67) TGM2NT5EKRASFUT5P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 — — EP claimed
CN-120020261-A Method for total synthesis of N-glycan 中国科学院上海药物研究所 2025-05-20 — — CN claimed
WO-2025019764-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS MATTERWORKS INC (US) 2025-01-23 — — WO claimed
US-20240418701-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2024-12-19 — — US claimed
CN-119120439-A UDP/GDP-glucose epimerase for catalytic synthesis of UDP/GDP-mannose 江南大学 2024-12-13 — — CN claimed
EP-4437319-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION Matterworks Inc (US) 2024-10-02 — — EP claimed
EP-4413379-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE Nanjing University (CN) 2024-08-14 — — EP claimed
CN-118103711-A Single molecule identification with reactive heterogeneous nanopores 南京大学 2024-05-28 — — CN claimed
CN-117683833-A Method for preparing nucleotide sugar from nucleoside monophosphate 山东大学 2024-03-12 — — CN claimed
CN-117187344-A HPLC method for measuring activity of polyterpene alcohol phosphomannosyltransferase 济宁医学院 2023-12-08 — — CN claimed
US-20230060588-A1 METHODS OF AMELIORATING AND/OR PREVENTING CORONAVIRUS-RELATED INFECTIONS Glycure LLC (US) 2023-03-02 — — US claimed
CN-114207108-A Genetically modified host cells producing glycosylated cannabinoids 奥克塔林生物制剂公司 2022-03-18 — — CN claimed
CN-111793664-A Method for biologically preparing mannose glyceric acid 中国科学院天津工业生物技术研究所 2020-10-20 — — CN claimed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 — — US claimed
WO-2005116230-A2 GOLGI APPARATUS REGENERATED IN VITRO METHOD FOR PRODUCTION AND USE THEREOF UNIVERSITE DE PROVENCE (FR) 2005-12-08 — — WO claimed
US-20020068331-A1 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose WONG CHI-HUEY (US) 2002-06-06 — — US claimed
EP-0642526-B1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE SCRIPPS RESEARCH INST (US) 1998-12-23 — — EP claimed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 — — EP claimed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 — — EP claimed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060588-A1 METHODS OF AMELIORATING AND/OR PREVENTING CORONAVIRUS-RELATED INFECTIONS FUT5, FUT6, SIGLEC7 TGM2 908/4885NT5E 378/4885KRAS 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.