Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | KRAS | P01116 | 6/20 | 0.61 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL2182862 | 1.00 | TGM2 (0.66) | TGM2NT5EKRASFUT5P2RY6 | |
| Galactose SCHEMBL6046113 | 1.00 | TGM2 (0.66) | TGM2NT5EKRASFUT5P2RY6 | |
| Demannose SCHEMBL20746287 | 1.00 | TGM2 (0.66) | TGM2NT5EKRASFUT5P2RY6 | |
| Demannose SCHEMBL4290630 | 1.00 | TGM2 (0.66) | TGM2NT5EKRASFUT5P2RY6 | |
| Xylose SCHEMBL1422097 | 0.98 | TGM2 (0.67) | TGM2NT5EKRASFUT5P2RY6 | |
| Guanosine Triphosphate SCHEMBL27608840 | 0.97 | TGM2 (0.66) | TGM2NT5EKRASFUT5P2RY6 | |
| Guanosine Triphosphate SCHEMBL29280175 | 0.95 | TGM2 (0.68) | TGM2NT5EKRASFUT5P2RY6 | |
| Guanosine Triphosphate SCHEMBL28337848 | 0.93 | TGM2 (0.60) | TGM2NT5EKRASFUT5P2RY6 | |
| L-Fucose SCHEMBL18992533 | 0.92 | TGM2 (0.67) | TGM2NT5EKRASFUT5P2RY6 | |
| L-Fucose SCHEMBL20607674 | 0.92 | TGM2 (0.67) | TGM2NT5EKRASFUT5P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886640-B1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | GLYCOMIMETICS INC (US) | 2007-03-21 | — | — | EP | disclosed |
| US-6169077-B1 | A SIALYLATED AND FUCOSYLATED CARBOHYDRATE; USE AS ANTIADHESION THERAPEUTICS TREATING INFLAMMATIONS, THEY CAN PREVENT THE SELECTIN RECEPTORS FROM BINDING TO ACTIVATED ENDOTHELIAL CELLS ON THE SURFACE OF LEUCOCYTES | GLYCOTECH CORP. | 2001-01-02 | — | — | US | disclosed |
| EP-0886640-A1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | GlycoTech Corp. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997028173-A1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | NOVARTIS AG (CH) | 1997-08-07 | — | — | WO | disclosed |