Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | AQP1 | P29972 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18993702 | 0.93 | ALDH1A1 (0.61) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL2741873 | 0.88 | CA2 (0.68) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL13283807 | 0.87 | ALDH1A1 (0.61) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL18993748 | 0.86 | ALDH1A1 (0.46) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL19300067 | 0.83 | ALDH1A1 (0.61) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL2741867 | 0.83 | KDM4E (0.72) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL2741865 | 0.82 | KDM4E (0.71) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL21018922 | 0.81 | LMNA (0.50) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL18993700 | 0.81 | ALDH1A1 (0.59) | ALDH1A1BLMCA2KDM4EUSP2 | |
| SCHEMBL19300066 | 0.81 | HPGD (0.61) | ALDH1A1BLMCA2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682928-B2 | Bumetanide analogs, compositions and methods of use | NEUROPRO THERAPEUTICS, INC. (US) | 2017-06-20 | — | — | US | disclosed |