SCHEMBL1899861

SCHEMBL1899861

CCCCCC(Cc1nnn[nH]1)C(=O)C(CCCCC)Cc1nnn[nH]1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.37
MAPK1 P28482 1/20 0.36
CA1 P00915 5/20 0.35
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
GPR84 Q9NQS5 3/20 0.32
FFAR1 O14842 1/20 0.32
TSHR P16473 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25139958 0.81 CA2 (0.37) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL22361547 0.81 CA2 (0.39) CA2GRIK1GRIK2SLC1A2SLC1A1
SCHEMBL1897437 0.80 GPR84 (0.36) GPR84FFAR1MAPT
SCHEMBL24040220 0.79 CA2 (0.41) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL531738 0.70 CA2 (0.60) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL10884513 0.70 CA2 (0.58) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL7095906 0.70
SCHEMBL2937529 0.68 CA2 (0.58) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL7654397 0.68 CA2 (0.58) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL7650538 0.68 CA2 (0.58) CA2MAPK1CA1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434970-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-09-06 US disclosed
US-20150252398-A1 METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER SK BIOPHARMACEUTICALS CO LTD (KR) 2015-09-10 US disclosed
US-9068207-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2015-06-30 US disclosed
US-20140073018-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2 Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2014-03-13 US disclosed
US-8404461-B2 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester SK Biopharmaceutical Co. Ltd. (KR) 2013-03-26 US disclosed
US-20110111467-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester SK BIOPHARMACEUTICALS CO. LTD. (KR) 2011-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110111467-A1 Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester CES1, ADH1A, ADH1C CA2 561/4885MAPK1 3423/4885CA1 195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.