SCHEMBL1899986

SCHEMBL1899986

CC(C)(C)[Si](C)(C)OC=Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.38
MAOB P27338 1/20 0.38
IDO1 P14902 2/20 0.37
CYP2C19 P33261 1/20 0.37
CMA1 P23946 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
EGFR P00533 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CHAT P28329 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1934370 0.81 CYP2C19 (0.38) MAOBCYP2C19MEN1KMT2AKDM4E
SCHEMBL7207745 0.80 TDP1 (0.33) TRPA1MAOBIDO1CYP2C19MEN1
SCHEMBL6419016 0.80 IDO1 (0.42) IDO1MEN1KMT2AKDM4ERELA
SCHEMBL10682846 0.79 MAOB (0.44) TRPA1MAOBCYP2C19MEN1KMT2A
SCHEMBL770392 0.79 MAOB (0.44) TRPA1MAOBCYP2C19MEN1KMT2A
SCHEMBL456141 0.74 TRPA1 (0.44) TRPA1MAOBCYP2C19CMA1MEN1
SCHEMBL9699570 0.74 TRPA1 (0.53) TRPA1CYP2C19MEN1KMT2AKDM4E
SCHEMBL19548024 0.73 RELA (0.43) TRPA1MAOBIDO1CYP2C19MEN1
SCHEMBL7395928 0.73 IDO1 (0.55) MAOBIDO1MEN1KMT2AHSD17B10
SCHEMBL2598224 0.73 MAOB (0.47) MAOBIDO1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853327-B1 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES BOSTON SCIENT LTD (BB) 2012-11-07 EP claimed
EP-1853327-A2 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES Boston Scientific Limited (BB) 2007-11-14 EP claimed
WO-2006083628-A2 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES BOSTON SCIENTIFIC SCIMED, INC. (US) 2006-08-10 WO claimed
US-20060171981-A1 Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species BOSTON SCIENTIFIC SCIMED, INC. 2006-08-03 US claimed
US-5914219-A Radiation-sensitive mixture and the production of relief structures having improved contrast BASF AKTIENGESELLSCHAFT (DE) 1999-06-22 US claimed
EP-0616258-B1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF AG (DE) 1997-05-21 EP claimed
EP-0616258-A1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF Aktiengesellschaft (DE) 1994-09-21 EP claimed
WO-2024066848-A1 HIGH-MOLECULAR-WEIGHT NARROW-DISTRIBUTION PHS RESIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海八亿时空先进材料有限公司 2024-04-04 WO disclosed
WO-2024020780-A1 STAR-SHAPED POLYMER, PAINT, COATING, AND METHOD FOR PRODUCING STAR-SHAPED POLYMER DIC CORPORATION (JP) 2024-02-01 WO disclosed
WO-2022236548-A1 STAR POLYMER, COATING MATERIAL, COATING FILM, AND METHOD FOR PRODUCING STAR POLYMER DIC CORPORATION (JP) 2022-11-17 WO disclosed
US-20180211828-A1 COMPOSITION FOR FORMING FILM FOR USE IN CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD FOR SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2018-07-26 US disclosed
US-8992512-B2 Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species BOSTON SCIENTIFIC SCIMED, INC. (US) 2015-03-31 US disclosed
EP-1853327-B1 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES BOSTON SCIENT LTD (BB) 2012-11-07 EP disclosed
US-5362597-A Lenses JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-11-08 US disclosed
EP-0616258-A1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF Aktiengesellschaft (DE) 1994-09-21 EP disclosed
EP-0605856-A2 Process for the manufacture of p-hydroxystyrene polymers and use thereof BASF Aktiengesellschaft (DE) 1994-07-13 EP disclosed
EP-0520626-A1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-30 EP disclosed
EP-0277555-B1 COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES BASF Aktiengesellschaft (DE) 1992-04-08 EP disclosed
US-4808682-A BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
EP-0277555-A2 Copolymers with 0-nitrocarbinol ester groups, and process for preparing two-layer resists and semiconductor devices BASF Aktiengesellschaft (DE) 1988-08-10 EP disclosed