Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219341 | 0.76 | RAB9A (0.56) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL17074602 | 0.76 | RAB9A (0.85) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL1461789 | 0.76 | RAB9A (1.00) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL13219314 | 0.75 | MAPT (0.72) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL1460657 | 0.75 | NPBWR1 (0.60) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL23402338 | 0.75 | USP2 (0.47) | RAB9AMAPTALDH1A1GAANPSR1 | |
| SCHEMBL19000712 | 0.75 | MAPT (0.52) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL14468578 | 0.74 | NR4A3 (0.51) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| Pyrazon SCHEMBL1858918 | 0.73 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTALDH1A1HTT | |
| Pyrazon SCHEMBL53824 | 0.73 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | BAK1, DCLRE1B, BLVRB | RAB9A 3085/4885SMN1; SMN2 4088/4885MAPT 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.