SCHEMBL19001545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3638924	0.81	TP53 (0.45)	PDE10ATP53AKT1AKT2PDE2A
	SCHEMBL1163063	0.78	MAPT (0.50)	PDE10ATP53AKT1AKT2KDM4E
	SCHEMBL25781181	0.77	PDE10A (0.42)	PDE10ANPSR1TP53AKT1AKT2
	SCHEMBL19054144	0.77	KDM4E (0.47)	PDE10ANPSR1TP53AKT1AKT2
	SCHEMBL13052928	0.77	TP53 (0.51)	PDE10ANPSR1TP53AKT1AKT2
	SCHEMBL3641378	0.77	TP53 (0.45)	PDE10ANPSR1TP53AKT1AKT2
	SCHEMBL18347135	0.77	PDE10A (0.42)	PDE10ANPSR1TP53AKT1AKT2
	Ammonia Solution, Strong SCHEMBL17962224	0.77	MAPT (0.49)	PDE10ATP53AKT1AKT2KDM4E
	SCHEMBL13052922	0.74	PDE10A (0.56)	PDE10ATP53AKT1AKT2MAPT
	SCHEMBL1106498	0.74	CSNK1E (0.47)	PDE10ANPSR1TP53AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.