Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003261 | 0.82 | MMP1 (0.59) | EGFRALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL19003298 | 0.81 | EGFR (0.49) | EGFRTP53ALDH1A1CYP2C19MAPT | |
| SCHEMBL19003351 | 0.80 | LMNA (0.50) | EGFRALDH1A1CYP2C19KMT2AMAPT | |
| SCHEMBL19003255 | 0.79 | EGFR (0.47) | EGFRTP53KMT2AMAPTMEN1 | |
| SCHEMBL19003254 | 0.78 | EGFR (0.53) | EGFRTP53ALDH1A1KMT2AMAPT | |
| SCHEMBL19003464 | 0.76 | EGFR (0.53) | EGFRTP53ALDH1A1KMT2AMAPT | |
| SCHEMBL31058631 | 0.76 | EGFR (0.75) | EGFRTP53RAB9AMMP1MMP2 | |
| SCHEMBL19003251 | 0.72 | EGFR (0.68) | EGFRTP53ALDH1A1CYP2C19KMT2A | |
| SCHEMBL19003354 | 0.72 | MMP1 (0.62) | EGFRALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL19003259 | 0.71 | MEN1 (0.52) | ALDH1A1KMT2AMAPTMEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |