Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 14/20 | 0.54 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003250 | 0.85 | MAPT (0.51) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19003248 | 0.83 | LMNA (0.56) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19003274 | 0.82 | MMP1 (0.58) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19003283 | 0.81 | RAB9A (0.52) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19003257 | 0.80 | KDM4E (0.49) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19003350 | 0.80 | ALDH1A1 (0.47) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3048659 | 0.80 | MAPT (0.59) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3048661 | 0.80 | MAPT (0.59) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19003244 | 0.79 | MAOB (0.51) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL19003253 | 0.79 | MAOB (0.56) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |