Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003264 | 0.80 | NR4A1 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19003250 | 0.78 | MAPT (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18985271 | 0.77 | CA12 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL19003348 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL19003248 | 0.76 | LMNA (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19003274 | 0.75 | MMP1 (0.58) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL19003283 | 0.74 | RAB9A (0.52) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19003257 | 0.73 | KDM4E (0.49) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19003252 | 0.73 | RAB9A (0.53) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19003244 | 0.72 | MAOB (0.51) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |