Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ATF4 | P18848 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003257 | 0.79 | KDM4E (0.49) | KDM4EHTTL3MBTL1RAB9AMEN1 | |
| SCHEMBL19003248 | 0.77 | LMNA (0.56) | KDM4EHTTL3MBTL1RAB9AMEN1 | |
| SCHEMBL19003250 | 0.76 | MAPT (0.51) | KDM4EHTTL3MBTL1RAB9AMEN1 | |
| SCHEMBL19003283 | 0.75 | RAB9A (0.52) | KDM4EHTTRAB9AMEN1KMT2A | |
| SCHEMBL19003243 | 0.74 | MAPT (0.61) | KDM4ERAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19003244 | 0.73 | MAOB (0.51) | KDM4EHTTRAB9AMEN1KMT2A | |
| SCHEMBL19003274 | 0.73 | MMP1 (0.58) | KDM4EHTTRAB9AMEN1KMT2A | |
| SCHEMBL19003264 | 0.73 | NR4A1 (0.56) | HTTL3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL19003253 | 0.73 | MAOB (0.56) | HTTL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19003249 | 0.72 | EGFR (0.42) | HTTL3MBTL1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |