Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443847 | 1.00 | LMNA (0.52) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL1101650 | 1.00 | LMNA (0.52) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL20824955 | 0.87 | ALDH1A1 (0.52) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL5235095 | 0.81 | KMT2A (0.64) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL6289914 | 0.81 | KMT2A (0.64) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL7911619 | 0.81 | KMT2A (0.64) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL845363 | 0.79 | CA2 (0.61) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL845362 | 0.79 | CA2 (0.61) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL19958893 | 0.79 | LMNA (0.57) | LMNAL3MBTL1CA2KMT2AALDH1A1 | |
| SCHEMBL4256710 | 0.79 | CA2 (0.61) | LMNAL3MBTL1CA2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322675-A1 | Pesticidally Active Heterocyclic Derivatives with Sulfer Containing Substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-24 | — | — | US | disclosed |
| US-20170174675-A9 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator | VERTEX PHARMACEUTICALS INCORPORATED | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174675-A9 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator | CFTR, SCNN1G, SCNN1B | LMNA 4048/4885L3MBTL1 4354/4885CA2 1110/4885 |
| US-20190322675-A1 | Pesticidally Active Heterocyclic Derivatives with Sulfer Containing Substituents | DDT, ACHE, SQOR | LMNA 3830/4885L3MBTL1 2780/4885CA2 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.