Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591711 | 0.79 | ENPP2 (0.52) | ENPP2 | |
| SCHEMBL27777602 | 0.78 | GAA (0.45) | GAAPSIP1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL17290260 | 0.78 | GAA (0.45) | GAAPSIP1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5178148 | 0.77 | LMNA (0.50) | GAATDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17748862 | 0.76 | GAA (0.44) | GAAPSIP1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL193882 | 0.76 | GAA (0.44) | GAAPSIP1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10944302 | 0.75 | CA9 (0.54) | KMT2AALDH1A1CA2MEN1RAB9A | |
| SCHEMBL6389945 | 0.75 | CA2 (0.52) | GAAKMT2ATDP1CYP2C19ALDH1A1 | |
| SCHEMBL28854341 | 0.73 | GAA (0.41) | GAAPSIP1ALDH1A1POLBRORC | |
| SCHEMBL10455034 | 0.72 | PSIP1 (0.74) | GAAPSIP1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0978015-B1 | LIGHT ABSORBING POLYMERS | AZ ELECTRONIC MATERIALS USA (US) | 2007-06-13 | — | — | EP | claimed |
| CN-1160599-C | Light-absorbing polymers | 克拉里安特国际有限公司 | 2004-08-04 | — | — | CN | claimed |
| US-5994430-A | POLYMER CONTAINING A UNSATURATED PHENOL COMPOUND | CLARIANT FINANCE BVI) LIMITED (VG) | 1999-11-30 | — | — | US | claimed |
| US-5981145-A | CONTAINING A COPOLYMER OF MODIFIED HYDROXYSTYRENE MONOMER AND AN ETHYLENICALLY UNSATURATED MONOMER FREE OF AROMATIC RING, SUITABLE FOR ANTIREFLECTIVE COATING | CLARIANT FINANCE (BVI) LIMITED (VG) | 1999-11-09 | — | — | US | claimed |
| US-8455477-B2 | Therapeutic compounds | MERCK SHARP & DOHME CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110207711-A1 | Therapeutic Compounds | MSD K.K. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2320907-A1 | THERAPEUTIC COMPOUNDS | Merck & Co., Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010017047-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-0978015-B1 | LIGHT ABSORBING POLYMERS | AZ ELECTRONIC MATERIALS USA (US) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207711-A1 | Therapeutic Compounds | WEE2, MARK3, WEE1 | GAA 2408/4885PSIP1 2668/4885KMT2A 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.