Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978386 | 0.78 | — | — | |
| SCHEMBL7978249 | 0.75 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL19005642 | 0.69 | SLC18A3 (0.35) | SLC18A3 | |
| SCHEMBL19005733 | 0.68 | CHRNB4 (0.40) | DRD2L3MBTL3 | |
| SCHEMBL19005791 | 0.66 | PDPK1 (0.33) | DRD2ADRA1A | |
| SCHEMBL19005737 | 0.62 | KDM4E (0.44) | DRD2MBTD1L3MBTL3HSD11B1ADRA1A | |
| SCHEMBL31505420 | 0.61 | — | — | |
| SCHEMBL17132902 | 0.61 | MBTD1 (0.34) | SLC18A3SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL17125726 | 0.61 | MBTD1 (0.34) | SLC18A3SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL17132900 | 0.61 | MBTD1 (0.34) | SLC18A3SIGMAR1MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |