Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978386 | 0.79 | — | — | |
| SCHEMBL19005661 | 0.75 | DRD2 (0.37) | SIGMAR1 | |
| SCHEMBL19005642 | 0.62 | SLC18A3 (0.35) | — | |
| SCHEMBL10092844 | 0.62 | — | — | |
| SCHEMBL19005733 | 0.61 | CHRNB4 (0.40) | — | |
| SCHEMBL31505420 | 0.55 | — | — | |
| SCHEMBL24365456 | 0.55 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL29082372 | 0.55 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL1083195 | 0.54 | ALDH1A1 (0.37) | — | |
| SCHEMBL24696611 | 0.54 | MAPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |