Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PRPS1 | P60891 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005661 | 0.66 | DRD2 (0.37) | DRD2ADRA1A | |
| SCHEMBL17132900 | 0.56 | MBTD1 (0.34) | — | |
| SCHEMBL17125726 | 0.56 | MBTD1 (0.34) | — | |
| SCHEMBL17132902 | 0.56 | MBTD1 (0.34) | — | |
| SCHEMBL14326147 | 0.55 | L3MBTL3 (0.37) | — | |
| SCHEMBL9596534 | 0.55 | L3MBTL3 (0.37) | — | |
| SCHEMBL9596519 | 0.55 | L3MBTL3 (0.37) | — | |
| SCHEMBL10197304 | 0.55 | MBTD1 (0.37) | — | |
| SCHEMBL9596527 | 0.55 | L3MBTL3 (0.37) | — | |
| SCHEMBL16763803 | 0.55 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |