Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005986 | 0.87 | CSNK2A1 (0.34) | RAB9AMAPTLMNATP53ALOX15 | |
| SCHEMBL19005974 | 0.71 | LMNA (0.38) | MAPTNPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL996979 | 0.70 | TUBB4A (0.52) | RAB9ANPC1MAPTLMNATP53 | |
| SCHEMBL996642 | 0.69 | TNFRSF1A (0.48) | MAPTLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL996646 | 0.69 | TNFRSF1A (0.48) | MAPTLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18987395 | 0.67 | CHRM4 (0.37) | LMNAKDM4EALDH1A1 | |
| SCHEMBL19005989 | 0.67 | HDAC1 (0.37) | MAPTNPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL16154028 | 0.67 | ERN1 (0.40) | RAB9AMAPTLMNATSHRSMN1; SMN2 | |
| SCHEMBL23070366 | 0.64 | PSEN1 (0.46) | RAB9ANPC1LMNATSHRSMN1; SMN2 | |
| SCHEMBL997205 | 0.64 | CA9 (0.40) | RAB9ANPC1MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |