Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 10/20 | 0.33 |
| ▸ | HTR2B | P41595 | 6/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005916 | 0.87 | RAB9A (0.31) | TP53LMNAALOX15TSHRRAB9A | |
| SCHEMBL19005967 | 0.76 | GAA (0.36) | TP53SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL19005974 | 0.71 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL19005965 | 0.70 | CSNK2A1 (0.35) | CSNK2A1HTR2CHTR2BHTR2ANOS3 | |
| SCHEMBL996977 | 0.68 | TUBB4A (0.52) | TP53LMNAALOX15TSHRRAB9A | |
| SCHEMBL19005989 | 0.67 | HDAC1 (0.37) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL19005997 | 0.67 | SIGMAR1 (0.34) | TP53SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL19006001 | 0.66 | CSNK2A1 (0.37) | CSNK2A1HTR2CHTR2BHTR2ANOS3 | |
| SCHEMBL17959498 | 0.64 | CSNK2A1 (0.42) | CSNK2A1HTR2CHTR2ANOS3NOS1 | |
| SCHEMBL15345637 | 0.63 | TLR8 (0.54) | CSNK2A1HTR2CHTR2BNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |