Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987392 | 0.94 | LARS1 (0.35) | HTR1ASLC6A4MTNR1AMTNR1BPDE4A | |
| SCHEMBL19005991 | 0.92 | MTNR1A (0.34) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL19005960 | 0.84 | REN (0.34) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL19005918 | 0.82 | HTR1A (0.38) | HTR1ASLC6A4MTNR1AMTNR1BPOLB | |
| SCHEMBL19006008 | 0.80 | HDAC1 (0.36) | HDAC1HDAC2POLBMAPTTSHR | |
| SCHEMBL19005915 | 0.79 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DREN | |
| SCHEMBL19005961 | 0.78 | REN (0.36) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL18987377 | 0.78 | REN (0.36) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL18987254 | 0.78 | MAPT (0.37) | HTR1ASLC6A4POLBMAPTSMN1; SMN2 | |
| SCHEMBL19005967 | 0.74 | GAA (0.36) | MTNR1AMTNR1BPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |