Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 7/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473319 | 0.84 | GABRA3 (0.42) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL20545136 | 0.82 | GABRA3 (0.41) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL19006550 | 0.81 | GABRA1 (0.40) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL11869795 | 0.81 | GABRA1 (0.53) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL19006771 | 0.78 | GABRA3 (0.66) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL11824906 | 0.75 | GABRA5 (0.51) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL19006762 | 0.74 | GABRA1 (0.43) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL14328999 | 0.72 | GABRA5 (0.48) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| SCHEMBL11828460 | 0.72 | CYP2C9 (0.49) | GABRA2GABRA1GABRA5GABRB2GABRA3 | |
| Acetic Acid SCHEMBL11828455 | 0.71 | GABRA1 (0.47) | GABRA2GABRA1GABRA5GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101808-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |