Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 11/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.66 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828965 | 0.86 | GABRA3 (0.73) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL29783033 | 0.86 | GABRA3 (0.73) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL11732204 | 0.82 | GABRA3 (0.64) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL11713247 | 0.81 | GABRA3 (0.63) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL11834518 | 0.81 | GABRA3 (0.63) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL11624016 | 0.80 | GABRA1 (1.00) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL29385106 | 0.80 | GABRA1 (1.00) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL11865356 | 0.79 | GABRA1 (0.80) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL19006763 | 0.78 | GABRA2 (0.47) | GABRA3GABRA2GABRA1GABRA5GABRB2 | |
| SCHEMBL7311148 | 0.78 | GABRA3 (0.70) | GABRA3GABRA2GABRA1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101808-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |