Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900085 | 0.92 | POLB (0.44) | POLBLMNANPSR1MAPTMAPK1 | |
| SCHEMBL1305579 | 0.73 | POLB (0.59) | POLBLMNANPSR1MAPTMAPK1 | |
| SCHEMBL7738531 | 0.73 | TSHR (0.44) | POLBLMNANPSR1MAPTMAPK1 | |
| SCHEMBL29846372 | 0.71 | NPSR1 (0.46) | POLBNPSR1MAPTMAPK1NR1I2 | |
| SCHEMBL7738533 | 0.71 | NR1I2 (0.53) | POLBLMNANPSR1MAPTNR1I2 | |
| SCHEMBL9714149 | 0.70 | POLB (0.45) | POLBLMNANPSR1MAPTNR1I2 | |
| SCHEMBL24371342 | 0.70 | MEN1 (0.49) | POLBLMNANPSR1MAPTNR1I2 | |
| SCHEMBL425583 | 0.69 | NR1I2 (0.54) | POLBLMNANPSR1MAPTMAPK1 | |
| SCHEMBL5734842 | 0.69 | POLB (0.73) | POLBLMNANPSR1MAPTMAPK1 | |
| SCHEMBL14981920 | 0.69 | TSHR (0.49) | POLBLMNANPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172855-A1 | Compositions With Controlled Network Structure | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-22 | — | — | US | disclosed |
| US-20170172855-A1 | Compositions With Controlled Network Structure | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172855-A1 | Compositions With Controlled Network Structure | NCLN, RAD51, SMCHD1 | POLB 429/4885LMNA 260/4885NPSR1 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.