Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312196 | 0.89 | NR1I2 (0.48) | NR1I2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL9714149 | 0.84 | POLB (0.45) | NR1I2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL425583 | 0.79 | NR1I2 (0.54) | NR1I2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL9300787 | 0.79 | ALDH1A1 (0.41) | NR1I2POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11318778 | 0.79 | SMN1; SMN2 (0.41) | NR1I2POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9300378 | 0.79 | LMNA (0.47) | POLBNPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13522913 | 0.78 | ALDH1A1 (0.51) | NR1I2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL16868493 | 0.77 | NPSR1 (0.58) | NR1I2POLBNPSR1ALDH1A1MAPT | |
| SCHEMBL11312216 | 0.77 | ALDH1A1 (0.47) | NR1I2POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7900085 | 0.75 | POLB (0.44) | NR1I2POLBNPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429329-B1 | PHOSPHONATION OF ALDEHYDE OR KETONE WITH HYDROCARBYL PHOSPHITE IN PRESENCE OF BASIC CATALYST TO FORM 1-HYDROXY HYDROCARBYLPHOSPHONATE; ESTERIFICATION WITH ACETIC ANHYDRIDE USING ACID CATALYST; CARBOXYLIC ACID REMOVAL | AKZO NOBEL NV (NL) | 2002-08-06 | — | — | US | disclosed |
| WO-1996024599-A1 | SYNTHESIS OF A HYDROCARBYLVINYL PHOSPHONIC ACID HYDROCARBYL ESTER | AKZO NOBEL N.V. (NL) | 1996-08-15 | — | — | WO | disclosed |
| US-4246103-A | INHIBIT PRECIPITATION OF HARD WATER IONS ESPECIALLY FOR INDUSTRIAL WATER AND SLUDGE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4071610-A | TREATMENT WITH PHOSPHONATE, PHOSPHATE, OR PHOSPHORAMIDE, HYDROGENATION, OXIDATION | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-31 | — | — | US | disclosed |