Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296451 | 0.82 | KMT2A (0.50) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL7900085 | 0.77 | POLB (0.44) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL19008259 | 0.73 | POLB (0.45) | POLBNPSR1MAPTALDH1A1NR1I2 | |
| SCHEMBL7738533 | 0.73 | NR1I2 (0.53) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL1305579 | 0.71 | POLB (0.59) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL9714149 | 0.71 | POLB (0.45) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL3908206 | 0.71 | SRC (0.45) | TSHRPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL649963 | 0.70 | TSHR (0.52) | TSHRPOLBNPSR1KCNH2ACHE | |
| SCHEMBL7512310 | 0.70 | LMNA (0.44) | TSHRPOLBNPSR1MAPTALDH1A1 | |
| SCHEMBL425583 | 0.70 | NR1I2 (0.54) | TSHRPOLBNPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429329-B1 | PHOSPHONATION OF ALDEHYDE OR KETONE WITH HYDROCARBYL PHOSPHITE IN PRESENCE OF BASIC CATALYST TO FORM 1-HYDROXY HYDROCARBYLPHOSPHONATE; ESTERIFICATION WITH ACETIC ANHYDRIDE USING ACID CATALYST; CARBOXYLIC ACID REMOVAL | AKZO NOBEL NV (NL) | 2002-08-06 | — | — | US | disclosed |
| WO-1996024599-A1 | SYNTHESIS OF A HYDROCARBYLVINYL PHOSPHONIC ACID HYDROCARBYL ESTER | AKZO NOBEL N.V. (NL) | 1996-08-15 | — | — | WO | disclosed |
| US-5116882-A | Process for making copolymers of vinyl aromatic monomers and vinyl phosphonic acid derivatives and foamed articles therefrom | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-05-26 | — | — | US | disclosed |
| US-5109033-A | Vinyl aromatic monomer/vinyl phosphonate copolymer compositions and foamed articles derived therefrom | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-04-28 | — | — | US | disclosed |