Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289237 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL7738533 | 0.84 | NR1I2 (0.53) | POLBNPSR1ALDH1A1NR1I2MAPT | |
| SCHEMBL17289013 | 0.83 | SMN1; SMN2 (0.43) | POLBALDH1A1NR1I2MAPTSMN1; SMN2 | |
| SCHEMBL9301199 | 0.83 | KMT2A (0.41) | POLBNPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL5402657 | 0.80 | SMN1; SMN2 (0.47) | POLBNPSR1ALDH1A1NR1I2MAPT | |
| SCHEMBL9300577 | 0.79 | LMNA (0.46) | POLBNPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16868493 | 0.76 | NPSR1 (0.58) | POLBNPSR1ALDH1A1NR1I2MAPT | |
| SCHEMBL2322359 | 0.76 | ALDH1A1 (0.40) | POLBNPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11312196 | 0.74 | NR1I2 (0.48) | POLBNPSR1ALDH1A1NR1I2MAPT | |
| SCHEMBL7900085 | 0.74 | POLB (0.44) | POLBNPSR1ALDH1A1NR1I2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493494-B2 | Phosphinine oxide derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
| US-5116882-A | Process for making copolymers of vinyl aromatic monomers and vinyl phosphonic acid derivatives and foamed articles therefrom | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-05-26 | — | — | US | disclosed |
| US-5109033-A | Vinyl aromatic monomer/vinyl phosphonate copolymer compositions and foamed articles derived therefrom | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | PHOSPHO1, PPIP5K2, ITPA | POLB 2599/4885NPSR1 820/4885ALDH1A1 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.