SCHEMBL19009850

SCHEMBL19009850

O=S(=O)(c1ccccc1)c1c2ccccc2c(-c2nc3c4ccccc4c4ccccc4c3c3c2ccc2ccccc23)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.35
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPRT1 P00492 1/20 0.31
G6PD P11413 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009847 0.87 HTR6 (0.36) HTR6ALDH1A1KDM4EHTTL3MBTL1
SCHEMBL19009856 0.83 MET (0.38) HTR6ALDH1A1G6PD
SCHEMBL19009857 0.82 HTR6 (0.36) HTR6ALDH1A1KDM4EHPRT1HTT
SCHEMBL19009862 0.79 HTR6 (0.38) HTR6ALDH1A1KDM4EG6PDHTT
SCHEMBL19009792 0.79 FFAR2 (0.35) HTR6ALDH1A1KDM4EHTTL3MBTL1
SCHEMBL19009848 0.77 HTR6 (0.37) HTR6ALDH1A1KDM4EHTTL3MBTL1
SCHEMBL19009791 0.76 FFAR2 (0.35) ALDH1A1KDM4EHTTL3MBTL1MEN1
SCHEMBL19009820 0.76 NPSR1 (0.32) ALDH1A1HPRT1MEN1USP2LMNA
SCHEMBL19021144 0.72 KDM4E (0.36) HTR6ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL19009779 0.71 FFAR2 (0.35) ALDH1A1KDM4EHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 HTR6 3859/4885ALDH1A1 163/4885KDM4E 3813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.