SCHEMBL19009863

SCHEMBL19009863

O=S(=O)(c1ccccc1)c1cccc(-c2ccc3c(c2)nc(-c2ccccc2)c2c4ccccc4c4ccccc4c32)n1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.34
TDP1 Q9NUW8 1/20 0.34
KAT6A Q92794 1/20 0.33
TTK P33981 1/20 0.32
FEN1 P39748 1/20 0.32
DHODH Q02127 2/20 0.31
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17300244 0.85 TTK (0.39) TDP1TTK
SCHEMBL17300245 0.83 TDP1 (0.41) TDP1TTKDHODHHTR6
SCHEMBL19009840 0.83 TDP1 (0.34) HSD11B1TDP1KAT6AHTR1AHTR2A
SCHEMBL19009780 0.82 KAT6A (0.35) HSD11B1KAT6ATTKFEN1HTR1A
SCHEMBL19846056 0.82 HSD11B1 (0.39) HSD11B1TDP1FEN1HTR6
SCHEMBL17300247 0.81 TDP1 (0.46) TDP1FEN1DHODHHTR6
SCHEMBL19009846 0.80 TDP1 (0.35) TDP1DHODHHTR6
SCHEMBL17300239 0.79 TTK (0.39) TDP1TTKDHODH
SCHEMBL19009810 0.79 HTR6 (0.36) TDP1FEN1HTR6
SCHEMBL17300234 0.78 HTR6 (0.42) TDP1DHODHHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 HSD11B1 873/4885TDP1 2848/4885KAT6A 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.