SCHEMBL19009780

SCHEMBL19009780

O=S(=O)(c1ccccc1)c1cccc(-c2ccc3c(c2)c(-c2ccccc2)nc2c4ccccc4c4ccccc4c32)n1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.35
HSD11B1 P28845 7/20 0.34
ERN1 O75460 1/20 0.33
TTK P33981 2/20 0.32
FEN1 P39748 1/20 0.32
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31
TERT O14746 1/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CNR2 P34972 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009782 0.84 HTR1A (0.33) KAT6AHSD11B1HTR1AHTR2AHTR7
SCHEMBL19846056 0.84 HSD11B1 (0.39) HSD11B1FEN1HTR6MEN1KMT2A
SCHEMBL19009863 0.82 HSD11B1 (0.34) KAT6AHSD11B1TTKFEN1HTR1A
SCHEMBL19009791 0.80 FFAR2 (0.35) TTKMEN1MAPTKMT2ASMN1; SMN2
SCHEMBL19009805 0.79 HTR6 (0.36) FEN1HTR1AHTR2AHTR7HTR6
SCHEMBL19009793 0.79 NPY1R (0.35) MAPT
SCHEMBL19009769 0.76 TOP1 (0.39) ERN1CNR2
SCHEMBL19846079 0.75 HSD11B1 (0.48) KAT6AHSD11B1HTR6MEN1KMT2A
SCHEMBL16369859 0.75 MEN1 (0.54) KAT6AHSD11B1HTR1AHTR2AHTR7
SCHEMBL19009840 0.74 TDP1 (0.34) KAT6AHSD11B1HTR1AHTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 KAT6A 2366/4885HSD11B1 873/4885ERN1 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.