Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126980 | 0.92 | POLB (0.48) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL4355804 | 0.92 | TSHR (0.54) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL19010409 | 0.90 | VCAM1 (0.47) | SMN1; SMN2PTGS2VCAM1PTGS1KMT2A | |
| SCHEMBL20408989 | 0.85 | ALDH1A1 (0.47) | TSHRSMN1; SMN2PTGS2VCAM1ALDH1A1 | |
| SCHEMBL17245005 | 0.85 | TSHR (0.49) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL10971715 | 0.85 | GAA (0.61) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL14932732 | 0.83 | ALDH1A1 (0.64) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8978670 | 0.83 | RAPGEF4 (0.56) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL10971647 | 0.83 | ALDH1A1 (0.59) | TSHRSMN1; SMN2PTGS2KMT2AMEN1 | |
| SCHEMBL19010399 | 0.81 | MEN1 (0.46) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9855545-B2 | Porous cyclodextrin polymeric materials and methods of making and using same | CORNELL UNIVERSITY (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170173560-A1 | POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2017-06-22 | — | — | US | disclosed |