SCHEMBL4355804

SCHEMBL4355804

Cc1cc(S(=O)(=O)c2ccc(F)c(C)c2)ccc1F

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
VCAM1 P19320 1/20 0.52
PTGS2 P35354 3/20 0.51
PTGS1 P23219 1/20 0.50
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
CRHBP P24387 1/20 0.49
ATM Q13315 1/20 0.49
CRHR2 Q13324 1/20 0.49
HTT P42858 3/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19010396 0.92 TSHR (0.49) TSHRSMN1; SMN2VCAM1PTGS2PTGS1
SCHEMBL10971715 0.92 GAA (0.61) TSHRSMN1; SMN2VCAM1PTGS2PTGS1
SCHEMBL17245005 0.92 TSHR (0.49) TSHRSMN1; SMN2VCAM1PTGS2PTGS1
SCHEMBL8978670 0.90 RAPGEF4 (0.56) TSHRSMN1; SMN2VCAM1PTGS2PTGS1
SCHEMBL10971647 0.90 ALDH1A1 (0.59) TSHRSMN1; SMN2PTGS2KMT2AMEN1
SCHEMBL2329775 0.84 PTGS2 (0.64) TSHRSMN1; SMN2PTGS2PTGS1KMT2A
SCHEMBL17245004 0.84 VCAM1 (0.81) TSHRSMN1; SMN2VCAM1PTGS2KMT2A
SCHEMBL17245003 0.84 VCAM1 (0.81) TSHRSMN1; SMN2VCAM1PTGS2KMT2A
SCHEMBL19010399 0.84 MEN1 (0.46) TSHRSMN1; SMN2VCAM1PTGS2PTGS1
SCHEMBL3900014 0.83 PTGS2 (0.65) TSHRSMN1; SMN2PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
EP-1788649-B1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100167165-A1 COPOLYMER, POLYMER ELECTROLYTE, AND USE THEREOF SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-01 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
EP-1788649-A1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE Mitsui Chemicals, Inc. (JP) 2007-05-23 EP disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed