Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355804 | 0.90 | TSHR (0.54) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL10971715 | 0.87 | GAA (0.61) | RAPGEF4TSHRSMN1; SMN2PTGS2VCAM1 | |
| SCHEMBL17245005 | 0.87 | TSHR (0.49) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL10971647 | 0.85 | ALDH1A1 (0.59) | TSHRSMN1; SMN2PTGS2KMT2AMEN1 | |
| SCHEMBL19010396 | 0.83 | TSHR (0.49) | TSHRSMN1; SMN2PTGS2VCAM1PTGS1 | |
| SCHEMBL9756844 | 0.80 | RAPGEF4 (0.54) | RAPGEF4TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15460389 | 0.78 | LMNA (0.64) | RAPGEF4TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL896933 | 0.77 | RAPGEF4 (0.56) | RAPGEF4TSHRKMT2AMEN1GAA | |
| SCHEMBL2329775 | 0.76 | PTGS2 (0.64) | TSHRSMN1; SMN2PTGS2PTGS1KMT2A | |
| SCHEMBL17245003 | 0.76 | VCAM1 (0.81) | TSHRSMN1; SMN2PTGS2VCAM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177174-A | Branched aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-05 | — | — | US | claimed |
| EP-0411625-B1 | Method to produce poly(arylene sulfide/sulfone) polymer | PHILLIPS PETROLEUM CO (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5350834-A | Thermal stability and purity, zinc compound | PHILLIPS PETROLEUM COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| US-5298574-A | Copolymerizing in presence of n-methyl-2-pyrrolidone, sodium carbonate and sodium hydrogen sulfide | PHILLIPS PETROLEUM COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5298573-A | Poly(arylene sulfide sulfone)/poly(arylene sulfide ketone) block copolymers and preparation thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5286817-A | Poly(arylene sulfide)/poly(arylene sulfide sulfone) block copolymers and preparation thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| US-5268449-A | Containing arylene sulfide and arylene sulfonate segments | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5266674-A | Copolymers | PHILLIPS PETROLEUM COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
| US-5235034-A | Increased melt stability and decreased impurities | PHILLIPS PETROLEUM COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5177174-A | Branched aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| US-4774276-A | ZINC IONS TO IMPROVE MELT STABILITY OF POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0280325-A2 | Melt stabilization of poly (arylene sulfide sulfone) S | PHILLIPS PETROLEUM COMPANY (US) | 1988-08-31 | — | — | EP | disclosed |
| EP-0033906-B1 | PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1985-05-15 | — | — | EP | disclosed |
| US-4301274-A | BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING | PHILLIPS PETROLEUM COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| EP-0033906-A1 | Process for the production of aromatic sulfide/sulfone polymers | PHILLIPS PETROLEUM COMPANY (US) | 1981-08-19 | — | — | EP | disclosed |
| US-4127713-A | FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER | PHILLIPS PETROLEUM COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4125525-A | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4102875-A | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4070349-A | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4016145-A | SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE | PHILLIPS PETROLEUM COMPANY (US) | 1977-04-05 | — | — | US | disclosed |