Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779826 | 0.93 | ENPP3 (0.32) | — | |
| SCHEMBL24974327 | 0.90 | NR1I2 (0.33) | — | |
| SCHEMBL25106939 | 0.86 | ENPP3 (0.31) | — | |
| SCHEMBL20096318 | 0.77 | ENPP3 (0.34) | — | |
| SCHEMBL26524246 | 0.77 | ENPP3 (0.32) | — | |
| SCHEMBL21236452 | 0.69 | ATP4A (0.33) | — | |
| SCHEMBL25898714 | 0.69 | GPR84 (0.32) | — | |
| SCHEMBL30079608 | 0.69 | — | — | |
| SCHEMBL14865768 | 0.68 | DNM1 (0.36) | — | |
| SCHEMBL23838524 | 0.68 | GPR88 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009433-B1 | 2-PHENYL-1,3-OXAZOLE AND 5-PHENYL-1,2,4-OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | DAIICHI SANKYO CO LTD (JP) | 2017-06-21 | — | — | EP | disclosed |