Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 6/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903992 | 0.90 | NAMPT (0.42) | PDPK1 | |
| SCHEMBL1902876 | 0.90 | BACE1 (0.40) | KLKB1CTSDPDPK1 | |
| SCHEMBL1907783 | 0.87 | PDPK1 (0.38) | PDPK1 | |
| SCHEMBL1899812 | 0.83 | MASP2 (0.39) | PDPK1 | |
| SCHEMBL1902464 | 0.83 | MASP2 (0.39) | PDPK1 | |
| SCHEMBL1901314 | 0.83 | KLKB1 (0.47) | CA2CA4VNN1KLKB1 | |
| SCHEMBL1903417 | 0.82 | EPHX2 (0.43) | PDPK1 | |
| SCHEMBL1901450 | 0.82 | MAPT (0.36) | PDPK1TRPV1 | |
| SCHEMBL1431876 | 0.81 | MASP2 (0.43) | PDPK1 | |
| SCHEMBL1431762 | 0.81 | MASP2 (0.43) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |