Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 9/20 | 0.51 |
| ▸ | CASP7 | P55210 | 6/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP9 | P55211 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015807 | 0.81 | CTSL (0.53) | CTSLCTSBCTSSCTSK | |
| SCHEMBL19015734 | 0.80 | CASP3 (0.54) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL7968958 | 0.80 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL7975507 | 0.80 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL9961861 | 0.80 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL18471610 | 0.80 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL19015812 | 0.75 | CYP1A2 (0.40) | — | |
| SCHEMBL7888191 | 0.74 | CTSK (0.53) | CASP3CASP1CTSLCTSBCTSS | |
| SCHEMBL19015891 | 0.74 | NPY5R (0.41) | CTSL | |
| SCHEMBL19015906 | 0.74 | CASP3 (0.80) | CASP3CASP7CASP1CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |