Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438891 | 0.81 | CHRNB2 (0.57) | CYP2D6CYP2C19SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1895297 | 0.81 | HTT (0.58) | SMN1; SMN2LMNA | |
| SCHEMBL1598660 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL17342606 | 0.79 | LMNA (0.43) | RIPK1PPIDRAB9ALMNAALDH1A1 | |
| SCHEMBL3427156 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNA | |
| SCHEMBL3057267 | 0.78 | BCHE (0.47) | RIPK1PPIDSMN1; SMN2RAB9ALMNA | |
| SCHEMBL17342588 | 0.78 | PADI3 (0.53) | CYP1A2CYP2D6CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL3806762 | 0.78 | EPHX2 (0.56) | PPIDCYP1A2CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL5803249 | 0.76 | NPC1 (0.62) | SMN1; SMN2RAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL29231816 | 0.76 | UTS2R (0.40) | RIPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059207-A2 | ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF | GREEN CROSS CORPORATION (KR) | 2011-05-19 | — | — | WO | disclosed |