Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677464 | 0.79 | LMNA (0.45) | RXRARXRBRXRGLMNAPTGS1 | |
| SCHEMBL1906822 | 0.75 | GABRA1 (0.34) | RXRARXRBRXRGLMNAPTGS1 | |
| SCHEMBL1369636 | 0.74 | RXRA (0.38) | RXRARXRBRXRGLMNAMEN1 | |
| SCHEMBL15067523 | 0.73 | ALDH1A1 (0.45) | LMNAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL28347509 | 0.73 | LMNA (0.42) | LMNAPTGS1HIF1AHTTPDK2 | |
| SCHEMBL17697657 | 0.72 | NPC1 (0.37) | LMNAMEN1PTGS2KMT2AMAPT | |
| SCHEMBL17810080 | 0.72 | RXRA (0.38) | RXRARXRBRXRGLMNAPTGS1 | |
| SCHEMBL7467097 | 0.71 | NPC1 (0.39) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL1451004 | 0.71 | ALDH1A1 (0.43) | LMNAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL8675449 | 0.71 | RXRA (0.45) | RXRARXRBRXRGLMNAPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319887-A1 | METHOD FOR MANUFACTURING MOLDED ARTICLE | Teijin Chemicals, Ltd. (JP) | 2011-05-11 | — | — | EP | disclosed |