Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907864 | 0.72 | ADRA2A (0.37) | — | |
| SCHEMBL2365632 | 0.72 | ADRA2A (0.37) | — | |
| SCHEMBL6653629 | 0.72 | ADRA2A (0.35) | PTPN1 | |
| SCHEMBL1094880 | 0.69 | HTR2C (0.48) | PTPN1 | |
| SCHEMBL2365775 | 0.69 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL6532681 | 0.67 | HTR2C (0.49) | — | |
| SCHEMBL6635416 | 0.67 | MTNR1B (0.38) | PTPN1 | |
| SCHEMBL2365900 | 0.67 | HTR2A (0.51) | PTPN1 | |
| SCHEMBL1095730 | 0.66 | HTR2A (0.34) | PTPN1 | |
| SCHEMBL1095117 | 0.64 | HTR2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322162-A1 | 5HT2C receptor modulator compositions and methods of use | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |