Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653629 | 0.76 | ADRA2A (0.35) | PTPN1 | |
| SCHEMBL1903335 | 0.69 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL1095362 | 0.64 | HTR2C (0.36) | — | |
| SCHEMBL2365632 | 0.64 | ADRA2A (0.37) | — | |
| SCHEMBL1095117 | 0.64 | HTR2A (0.38) | — | |
| SCHEMBL1901752 | 0.62 | HTR2C (0.69) | PTPN1 | |
| SCHEMBL1095399 | 0.62 | HTR2C (0.69) | PTPN1 | |
| SCHEMBL1095400 | 0.62 | HTR2C (0.69) | PTPN1 | |
| SCHEMBL6635416 | 0.62 | MTNR1B (0.38) | PTPN1 | |
| SCHEMBL1095730 | 0.62 | HTR2A (0.34) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363394-A1 | 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, its salts, solvates or hydrates and its use for the treatment of CNS disorders | Arena Pharmaceuticals, Inc. (US) | 2011-09-07 | — | — | EP | disclosed |