Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | NPY1R | P25929 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13446087 | 1.00 | HTR1A (0.61) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL19036167 | 1.00 | HTR1A (0.61) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL19036168 | 1.00 | HTR1A (0.61) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL8170772 | 0.93 | DRD2 (0.69) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL8511597 | 0.93 | DRD2 (0.69) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL8240610 | 0.93 | DRD2 (0.69) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL8169712 | 0.93 | DRD2 (0.69) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL13376761 | 0.89 | HTR1A (0.61) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL14459961 | 0.86 | DRD2 (0.72) | HTR1AMLNRADRB2ADRB1ADRA2A | |
| SCHEMBL13762734 | 0.86 | DRD2 (0.72) | HTR1AMLNRADRB2ADRB1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822090-B2 | Method for producing nebivolol hydrochloride of high purity | CORDEN PHARMA INTERNATIONAL GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-20170183323-A1 | A NEW METHOD FOR PRODUCING NEBIVOLOL HYDROCHLORIDE OF HIGH PURITY | CORDON PHARMA INTERNATIONAL GmbH (DE) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183323-A1 | A NEW METHOD FOR PRODUCING NEBIVOLOL HYDROCHLORIDE OF HIGH PURITY | ADRB2, ADRB1, ADRA2B | HTR1A 318/4885MLNR 1013/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.