SCHEMBL19038950

SCHEMBL19038950

CCCCC(CC)COC(=O)/C(C#N)=C\C=C1/CCCN1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.44
▸ LMNA P02545 6/20 0.44
▸ MAPK1 P28482 4/20 0.44
▸ MAPT P10636 8/20 0.40
▸ MEN1 O00255 7/20 0.40
▸ KMT2A Q03164 7/20 0.40
▸ GAA P10253 4/20 0.40
▸ CYP3A4 P08684 4/20 0.40
▸ POLB P06746 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ TSHR P16473 3/20 0.39
▸ RAB9A P51151 5/20 0.39
▸ NPC1 O15118 4/20 0.39
▸ USP2 O75604 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ NPSR1 Q6W5P4 3/20 0.39
▸ TDP1 Q9NUW8 3/20 0.38
▸ ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22484311 0.93 MAPT (0.44) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL27117352 0.92 MAPT (0.42) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL19240023 0.86 ALDH1A1 (0.43) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL19038917 0.81 MAPT (0.55) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL26338677 0.77 MEN1 (0.34) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL14768457 0.77 ALDH1A1 (0.48) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL19038893 0.77 MAPT (0.45) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL12101256 0.77 ALDH1A1 (0.48) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL14095054 0.77 ALDH1A1 (0.48) ALDH1A1LMNAMAPK1MAPTMEN1
SCHEMBL5563793 0.76 ALDH1A1 (0.46) ALDH1A1LMNAMAPK1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119687-A1 LAMINATE, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-04-21 — — US disclosed
US-20220119688-A1 LAMINATE, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-04-21 — — US disclosed
WO-2021045192-A1 COMPOSITION, POLARIZER LAYER, LAYERED PRODUCT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2021-03-11 — — WO disclosed
US-10690824-B2 Optical laminate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 — — US disclosed
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-24 — — US disclosed
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-24 — — US disclosed
US-20170184766-A1 OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170184766-A1 OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER MLN, MLEC, VIP ALDH1A1 1236/4885LMNA 335/4885MAPK1 4279/4885
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer MLN, MLEC, VIP ALDH1A1 1236/4885LMNA 335/4885MAPK1 4279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback