Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288287 | 0.96 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL20589913 | 0.96 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL9285562 | 0.96 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL23576154 | 0.96 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL12201188 | 0.93 | CASP2 (0.58) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL8723696 | 0.92 | SLC6A5 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL20588850 | 0.91 | DNM1 (0.49) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL8777387 | 0.91 | CASP2 (0.49) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL9290507 | 0.91 | NAAA (0.50) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL9289434 | 0.88 | CASP2 (0.46) | CASP2NAAAEPHX1DNM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |