Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667663 | 0.87 | EPHX2 (0.43) | EPHX2SCN9AKCNH2SCN5AKMT2A | |
| SCHEMBL28356770 | 0.85 | MTNR1A (0.45) | MTNR1A | |
| SCHEMBL22472834 | 0.80 | EPHX2 (0.59) | TP53EPHX2KMT2AL3MBTL1MTNR1A | |
| SCHEMBL877883 | 0.79 | KMT2A (0.39) | EPHX2SCN9AKCNH2SCN5AKMT2A | |
| SCHEMBL873945 | 0.79 | DRD2 (0.45) | SCN9AKCNH2SCN5AKMT2AL3MBTL1 | |
| SCHEMBL873946 | 0.79 | DRD2 (0.45) | SCN9AKCNH2SCN5AKMT2AL3MBTL1 | |
| SCHEMBL19667244 | 0.79 | KMT2A (0.47) | TP53EPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL28353342 | 0.77 | BTK (0.40) | EPHX2KMT2AL3MBTL1GAAMTNR1A | |
| SCHEMBL874562 | 0.76 | EPHX2 (0.43) | EPHX2KMT2AL3MBTL1GAAMTNR1A | |
| SCHEMBL882619 | 0.76 | SCN9A (0.67) | SCN9AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712129-A1 | ALPHA, BETA-UNSATURATED AMIDE COMPOUND | Kyowa Kirin Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |
| WO-2017111076-A1 | α, β UNSATURATED AMIDE COMPOUND | 協和発酵キリン株式会社 | 2017-06-29 | — | — | WO | disclosed |