Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.81 |
| ▸ | AR | P10275 | 1/20 | 0.81 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 1/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.81 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromhexine SCHEMBL19059 | 0.90 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL29379593 | 0.90 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL10704011 | 0.89 | LMNA (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL18548828 | 0.89 | CYP2D6 (0.97) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL99613 | 0.89 | LMNA (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL5968149 | 0.83 | CYP2D6 (0.81) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL11045765 | 0.80 | CYP2D6 (0.71) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL11286788 | 0.80 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL13907693 | 0.79 | CYP2D6 (0.79) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL11286390 | 0.79 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723501-A | Pharmaceutical compositions containing 3-IODO-1,2-propanediol having mucolytic activity | CARTER-WALLACE, INC. (US) | 1998-03-03 | — | — | US | disclosed |