Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19059295 | 0.93 | CYP11B2 (0.36) | CYP11B2HDAC9 | |
| SCHEMBL15492413 | 0.90 | CYP11B2 (0.36) | CYP11B2HDAC9 | |
| SCHEMBL15492457 | 0.88 | CYP11B2 (0.36) | CYP11B2HDAC9 | |
| SCHEMBL19059004 | 0.88 | HDAC9 (0.36) | CYP11B2HDAC9 | |
| SCHEMBL19059003 | 0.82 | CYP11B2 (0.40) | CYP11B2HDAC9 | |
| SCHEMBL9538975 | 0.79 | HDAC9 (0.41) | CYP11B2HDAC9 | |
| SCHEMBL35277 | 0.77 | — | — | |
| SCHEMBL29460883 | 0.77 | SIGMAR1 (0.43) | CYP11B2HDAC9 | |
| SCHEMBL29438246 | 0.77 | — | — | |
| SCHEMBL556889 | 0.77 | SIGMAR1 (0.43) | CYP11B2HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2693882-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK SHARP & DOHME (US) | 2017-06-28 | — | — | EP | disclosed |