Bilirubin

Bilirubin

SCHEMBL5493673

C=CC1=C(C)/C(=C/c2[nH]c(Cc3[nH]c(/C=C4\NC(=O)C(C)=C4C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)NC1=O.[CaH2]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.98
MEN1 O00255 1/20 0.98
ALDH1A1 P00352 1/20 0.98
LMNA P02545 1/20 0.98
MAPT P10636 1/20 0.98
CASP1 P29466 1/20 0.98
CASP7 P55210 1/20 0.98
KMT2A Q03164 1/20 0.98
HSD17B10 Q99714 1/20 0.98
SLCO1B3 Q9NPD5 1/20 0.98
TDP1 Q9NUW8 1/20 0.98
SLCO1B1 Q9Y6L6 1/20 0.98
P2RX7 Q99572 1/20 0.90
ABCC1 P33527 2/20 0.70
ABCC2 Q92887 2/20 0.70
KDR P35968 13/20 0.38
FGFR1 P11362 12/20 0.38
PDGFRB P09619 11/20 0.38
FLT3 P36888 3/20 0.38
AURKB Q96GD4 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bilirubin SCHEMBL3361472 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL5086205 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL10565617 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL19065 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL32671479 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL23529823 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL11412908 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL6735045 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL2942018 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL9116171 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060634-A Ox bile-resistant bezoar transformation strain and application thereof 中国药科大学 2026-05-19 CN claimed
CN-118873531-A Preparation method and application of artificial bezoar based on 3D printing 麒牛药业(珠海横琴)有限公司 2024-11-01 CN claimed
CN-118845839-A Method for preparing high-bionic bezoar by using 3D printing technology and application 麒牛药业(珠海横琴)有限公司 2024-10-29 CN claimed
CN-117959338-A In-vitro bionic cultivation method for bovine bilirubin stones 汉中青钱柳科技服务有限公司 2024-05-03 CN claimed
CN-117883476-A Artificial bezoar compounding process 浏阳利美医院有限公司 2024-04-16 CN claimed
CN-115837035-A In-vitro cultured bezoar and preparation method thereof 北京宏同堂制药有限公司 2023-03-24 CN claimed
CN-112656818-A Artificial bezoar and preparation method thereof 四川菲德力制药有限公司 2021-04-16 CN claimed
CN-111658671-A In-vitro cultured bezoar and preparation method thereof 武汉健民大鹏药业有限公司 2020-09-15 CN claimed
CN-111388132-A Bezoar generator for external gallbladder of cow and method for preparing bezoar by using bezoar generator 西安国联质量检测技术股份有限公司 2020-07-10 CN claimed
CN-106265742-A A kind of method of In vitro cultured Calculus Bovis 王昌勇 2017-01-04 CN claimed
CN-122060634-A Ox bile-resistant bezoar transformation strain and application thereof 中国药科大学 2026-05-19 CN disclosed
CN-122031527-A Method for cultivating bezoar by utilizing flora 中科桂投港务农业(贺州)有限公司 2026-05-15 CN disclosed
CN-118726139-B Lactobacillus plantarum and application thereof 福建中益制药有限公司 2025-05-02 CN disclosed
CN-118726138-B Lactobacillus brevis and application thereof 福建中益制药有限公司 2025-04-04 CN disclosed
CN-119745926-A Production method for in vitro cultivation of bezoar 四川微流控科技有限公司 2025-04-04 CN disclosed
CN-1347700-A Method of in vitro culturing medicine ox gallstone with natural ox gall WUHAN DAPENG PHARMACEUTICAL IN (CN) 2002-05-08 CN disclosed
WO-2001049301-A1 METHODS OF USING ELECTRON ACTIVE COMPOUNDS FOR MANAGING CANCER MARANTECH HOLDING, LLC (US) 2001-07-12 WO disclosed
EP-0497724-B1 An agent for disintegrating gallstones SENJU PHARMA CO (JP) 1996-03-27 EP disclosed
US-5441748-A Aqueous solution containing sodium hydrogen carbonate and N-acetylcysteine SENJU PHARMACEUTICAL CO., LTD. (JP) 1995-08-15 US disclosed
EP-0497724-A1 An agent for disintegrating gallstones Senju Pharmaceutical Co., Ltd. (JP) 1992-08-05 EP disclosed