SCHEMBL190703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL189840	0.79	RAB9A (0.59)	MCL1PARP10SMPD1XDHMEN1
	SCHEMBL222716	0.77	PARP10 (0.51)	MCL1PARP10SMPD1XDHGSTP1
	SCHEMBL6634107	0.77	PARP10 (0.68)	PARP10RAB9ASMN1; SMN2NR4A2LTA4H
	SCHEMBL190360	0.75	NR4A2 (0.51)	MCL1SMPD1XDHMEN1NPC1
	SCHEMBL189525	0.75	RAB9A (0.60)	MCL1SMPD1MEN1NPC1POLB
	SCHEMBL189580	0.74	RAB9A (0.52)	MCL1PARP10SMPD1XDHMEN1
	SCHEMBL27843564	0.74	NPC1 (0.58)	MCL1SMPD1MEN1NPC1POLB
	SCHEMBL16244407	0.73	SMPD1 (0.54)	MCL1PARP10SMPD1XDHMEN1
	SCHEMBL190096	0.72	FFAR1 (0.60)	PARP10SMPD1NPC1RAB9ASMN1; SMN2
	SCHEMBL28694024	0.71	PARP10 (0.64)	PARP10RAB9ASMN1; SMN2NR4A2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.