Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA5A | P35218 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138970 | 0.75 | CDK2 (0.78) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL222006 | 0.73 | KMT2A (0.54) | CDK2CA2CA1CA9CA5A | |
| SCHEMBL10577721 | 0.69 | CA2 (0.64) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL7942707 | 0.67 | ALDH1A1 (0.42) | CA2CA1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL15851423 | 0.66 | CDK2 (0.70) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL1804410 | 0.66 | CDK2 (0.64) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL29401806 | 0.66 | CDK2 (1.00) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL588923 | 0.66 | CDK2 (1.00) | CDK2CA2CA1CA9PNMT | |
| SCHEMBL1803500 | 0.66 | TTR (0.68) | CDK2CA2CA1CA9LDHA | |
| SCHEMBL9669785 | 0.66 | CDK2 (0.58) | CDK2CA2CA1CA9PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2317316-A2 | Methods for identifying agent and conditions that modulate neurogenesis | Braincells, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-1904843-A2 | METHODS FOR IDENTIFYING AGENTS AND CONDITIONS THAT MODULATE NEUROGENESIS | Braincells, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |
| US-20070015138-A1 | Methods for identifying agents and conditions that modulate neurogenesis | BRAINCELLS, INC. (US) | 2007-01-18 | — | — | US | disclosed |
| WO-2007008758-A2 | METHODS FOR IDENTIFYING AGENTS AND CONDITIONS THAT MODULATE NEUROGENESIS | BRAINCELLS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |